|
Symbol Name ID |
Hap1
huntingtin-associated protein 1 MGI:1261831 |
| Darker colors indicate more annotations |
| Human Phenotypes | Gliosis |
Cerebellar atrophy |
Neuronal loss in central nervous system |
Gait ataxia |
Bradykinesia |
Chorea |
Depression |
Personality changes |
Dementia |
Hyperreflexia |
Seizure |
| Disease(s) Associated with HAP1 | |||||||||||
| Huntington's disease |
| Mouse Phenotypes | impaired neuron differentiation |
abnormal neuron proliferation |
decreased brain weight |
decreased brain size |
abnormal hypothalamus morphology |
abnormal paraventricular hypothalamic nucleus morphology |
abnormal ventromedial hypothalamic nucleus morphology |
abnormal cerebral cortex morphology |
thin cerebral cortex |
abnormal neurite morphology |
neurodegeneration |
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| Availability | Mouse Genotype | |||||||||||
| Hap1tm1Hay/Hap1tm1Hay | ||||||||||||
| Hap1tm1Xjl/Hap1tm1Xjl | ||||||||||||
| Hap1tm2Xjl/Hap1tm2Xjl Tg(HCRT-cre)1Stak/0 (conditional) |
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| Hap1tm2Xjl/Hap1tm2Xjl Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
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| Hap1tm2Xjl/Hap1tm2Xjl Tg(Camk2a-cre)159Kln/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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